Researchers with the VA San Diego Healthcare System and the University of California San Diego have shown that a gene transfer technique can combat heart dysfunction caused by diabetes.Working with mice, the researchers showed that a single injection to promote the expression of the hormone urocortin 2 (UCn2) increased left ventricle function and improved how the
In case you haven’t heard: Exercise is really good for people with type 2 diabetes. It helps control blood sugar levels, increases energy levels, improves heart health, and promotes emotional well-being. Barring other medical complications, the majority of people with diabetes can and should exercise for diabetes control and for better overall health and
If you’re managing type 1 diabetes or have a loved one affected by the condition, you know that glycemic control can be a huge challenge. At times, it may seem like the slightest changes to your routine can throw your blood sugar completely out of whack. Insulin, food, and exercise all impact the control you have
Even though I have personally been living with diabetes since I was four years old (in 1968), I knew even back then—more than a decade before the era of home blood glucose monitoring began—that exercise did good things for my blood sugars.How could I tell without a meter? Mainly I knew because being active
A small U.S. study has found that women with type 1 diabetes still gave birth to larger babies despite good glycemic control using active diabetes management and continuous glucose monitoring.In the study, researchers examined whether there were trimester-specific associations with glycemic variations, fetal growth, and birthweight involving pregnancies with type 1 diabetes.
The retrospective cohort study involved
Patients on medication for Type 2 diabetes may be keeping Alzheimer’s disease away.University of Southern California Dornsife psychologists found that those patients with untreated diabetes developed signs of Alzheimer’s disease 1.6 times faster than people who did not have diabetes.
“Our findings emphasize the importance of catching diabetes or other metabolic diseases in adults as early
Older adults with Type 1 diabetes typically have low blood sugar, or hypoglycemia, for more than an hour a day, suggests new research.Those who are not aware their blood sugar is too low can spend more than 100 minutes a day in the hypoglycemic range, raising their risk of seizures, loss of consciousness and death.
The exact causes of type 1 diabetes are not yet known. But genetics, family history, and environmental factors appear to play a role in the development of this serious health condition. In this section, we’ll examine each of the potential causes.
Genetic Causes Of Type 1 Diabetes
Type 1 diabetes is a polygenic disease;
Type 1 diabetes mellitus (T1DM) is the most common metabolic endocrine disease in children. It is a clinical condition whereby a child’s pancreas stops producing an important hormone called insulin. Insulin is a hormone produced by the beta cells in the pancreas. It facilitates the entry of glucose into the cells and also plays a
It was March 2014 when I received a phone call as I was working in my office. The person on the other end introduced herself as Dr. Linda Houston-Feenstra, chief cardiac nurse of Loma Linda University SACHS Heart Clinic. She said that she has heard about my work on persuasive technology, in particular how it
Older adults need to eat more protein-rich foods when they’re trying to lose weight, dealing with a chronic or acute illness, or facing a hospitalization, according to a growing consensus among scientists.During these stressful periods, aging bodies process protein less efficiently and need more of it to maintain muscle mass and strength, bone health
When “Jeopardy!” episode 7059 aired on April 30, 2015, the category was “The Human Body,” the price was $2,000, and the clue was “This gland’s main duct, the duct of Wirsung, collects its juices & empties into the duodenum.”
The question was “What is the pancreas?” Unbeknownst to Alex Trebek, the show’s beloved host, the cells that line the
Diabetes is the seventh-leading cause of death in the U.S., with about 30.3 million adults having the disease. One in 4 adults does not even know he or she has diabetes. In addition, 84.1 million adults have prediabetes – a condition with elevated blood sugar levels – and 90 percent of them do not know they have it. The toll,
What Is Bydureon?
Bydureon is a member of the GLP-1 receptor agonist* family of medicines. Bydureon works in several places in the body, and addresses four different problems that may occur in people with diabetes. It works by supporting a system of hormones in the gut called the incretin system. These gut hormones are
Diabetes is a metabolic condition characterized by high sugar levels in the blood. This happens when the body doesn’t produce enough of the hormone “insulin” or it is not able to use the secreted insulin.
Insulin is secreted by a specialized group of cells from the pancreas called the “β- cells of islet of
Teens who sit for hours watching TV, using the computer or playing video games while eating unhealthy snacks are at increased risk for a group of risk factors for heart disease and diabetes, according to research from Brazil.The study found these teens are at risk of developing metabolic syndrome–a cluster of risk factors including
Type 1 diabetes diagnosed in adulthood may be a form of slowly-progressing diabetes called latent autoimmune diabetes in adults (LADA). LADA is also known as slow-onset type 1 diabetes, type 1.5 diabetes, late-onset autoimmune diabetes of adulthood, and even “double diabetes,” since it has elements of both type 1 and type 2 diabetes. LADA patients,
Most people are familiar with the more common forms of diabetes: type 1, type 2, and gestational diabetes. But, did you know there are other forms of the disease as well? Often, due to the complexity of the disease, it’s hard to diagnose and distinguish between the various forms. For starters, we will explore
Once you hit the big 4-0 things are not quite like they use to be, your metabolism slows and it’s not as easy as it used to be to lose weight. There are many reasons for this, including changes in hormones, your activity level and what you choose to eat. Here are a few
The hemoglobin A1c blood test, widely used to diagnose Type 1 and Type 2 diabetes, is actually unable to detect the disease in most patients, according to a new study by City of Hope researchers.The hemoglobin A1c test, also known as HbA1c, shows a person’s average level of blood sugar over the past two to three months.
Oramed Pharmaceuticals Inc., a company developing of oral drug delivery systems, announced today that its Chinese partner, Hefei Tianhui Incubator of Technologies Co., Ltd., has reached the significant regulatory milestone of approval of an investigational new drug application (IND) for two doses of its oral insulin (ORMD-0801).
The approval of the IND by the Center For
Walking downhill after eating can reduce bone resorption, the process in which old bone is broken down and removed from the body, in postmenopausal women with diabetes, according to new research. Walking uphill does not have the same benefit, the study found.
All women are at risk of bone loss after menopause because of
Did you know that people with diabetes can suffer from an eating disorder? It’s called diabulimia and refers to an eating disorder in which a person with diabetes, (usually Type I) restricts insulin in order to lose weight. The term, Eating Disorder-Diabetes Mellitus Type 1, or ED-DMT1, is the medical term used to refer to any type of eating
A blood test conducted as early as the 10th week of pregnancy may help identify women at risk for gestational diabetes, a pregnancy-related condition that poses potentially serious health risks for mothers and infants, according to researchers at the National Institutes of Health and other institutions.
Gestational diabetes occurs only during pregnancy and results when
Sometimes diabetes is diagnosed very early on in small babies, and researchers at the University of Helsinki are doing more to understand why, in hopes of one-day developing drugs for the prevention of this, and more common forms of diabetes. To understand the mechanisms better, the team in Finland was able to look at the mutations in the
Physical activity is an excellent tool for people with diabetes, but it must be done with a little planning and extra care. People with diabetes understand that physical activity is essential to leading a healthy life. It is an excellent tool for achieving weight loss, better glucose control, and cardiovascular health; however, before you start any new
We often hear from patients in the clinic here at Joslin Diabetes Center that wearing a medical emergency bracelet can be a bit of a nuisance. To begin with, it’s not exactly a fashion accessory, is it? Nevertheless, you should wear one. In fact, we can’t emphasize too much just how important it is
Many health benefits come with exercise. But not every type of exercise is suitable for those living with diabetes. Exercise can actually exacerbate some health problems associated with diabetes, especially those involving the feet.
Diabetes can cause nerve damage in the form of peripheral neuropathy, which presents itself as feelings of numbness, stiffness and/or burning
More than half of patients with type 2 diabetes using treatments other than insulin, may be using their test-strips incorrectly — testing when not necessary, according to a new report. “The aim of this study was to quantify the rate of use and cost of self-monitoring blood glucose supplies that are potentially used inappropriately, specifically focusing on
Scientists working to develop more effective treatments for diabetes are turning to stem cells. Such cells can be transformed into cells that produce insulin, the hormone that controls blood sugar. But there’s a major challenge: the amount of insulin produced by these cells is difficult to control.
Now, by tweaking the recipe for coaxing human stem
Senseonics Holdings, Inc., a medical technology company developing a long-term, implantable continuous glucose monitoring (CGM) system for people with diabetes, has announced the launch of a new patient program. Under the new the Eversense Bridge Program, patients can access the Eversense CGM System, the only long-term CGM that lasts up to 90 days, for
New findings from the University of California – Los Angeles Health Sciences finds the menopause transition phase, also known as perimenopause, is a period when women lose lean body mass and more than double their fat mass. Perimenopause is the time in a woman’s life when hormonal changes lead to irregular menstruation, hot flashes
DarioHealth Corp., a digital Therapeutics company, announced today the receipt of a license from Health Canada to sell its Dario™ Blood Glucose Monitoring System for Lightning power connector-enabled iPhone smart mobile devices. “Recognizing the importance of access to the entire iPhone market in Canada, we prioritized this initiative to meet Health Canada’s rigid licensing standards,
Spring is here, the sun is coming out and you may be itching to come out of winter hibernation. Let’s talk about Spring Break, a good time to catch up with children and grandchildren that may be near and far and maybe go on a little trip.
Whether you are going for a little
Senseonics Holdings, Inc., announced it will extend its agreement with Roche Diabetes Care to sell its implantable continuous glucose monitoring (CGM) system for people with diabetes, today to 17 other countries including Brazil, Russia, India, and China.
Under the agreement, Roche will continue its role as Senseonics exclusive distributor in Europe, the Middle East,
Senseonics Holdings, Inc. announced the integration of Eversense CGM data into the Glooko diabetes data management platform. Senseonics is focused on the development and commercialization of a long-term, implantable continuous glucose monitoring (CGM) system for people with diabetes.
This integration will allow Eversense CGM data to be synced into Glooko’s platform directly from the
Type 2 diabetes—previously referred to as adult-onset or non-insulin dependent diabetes—accounts for 90 to 95 percent of all diabetes cases in the United States.It’s characterized by the body’s inability to use insulin effectively. Insulin is a hormone produced by the pancreas that helps the body turn glucose into energy.
Unlike people with type 1 diabetes, who do
The U.S. Food and Drug Administration (FDA) has approved a label update for AstraZeneca’s FARXIGA® (dapagliflozin) and XIGDUO® XR (dapagliflozin and metformin HCl extended-release) expanding use in patients with Type 2 diabetes and moderate renal impairment.
FARXIGA is indicated as an adjunct to diet and exercise to improve glycemic control in adults with Type 2 diabetes. XIGDUO XR
The Centers for Disease Control reports that 15 percent of Americans living with type 2 diabetes struggle with hard-to-heal foot ulcers.Now, a biomedical engineering team at Michigan Tech wants to reduce how long it takes for diabetic foot ulcers to heal. They want to take the typical healing period from 150 to 21 days.
Carmot Therapeutics initiated a clinical trial for the treatment of type 2 diabetes with CT-868, a dual modulator of the GLP-1 and GIP incretin receptors.The phase 1 trial will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamic effects of CT-868 in overweight or obese but otherwise healthy volunteers and patients with type 2 diabetes, according to a
The cardiovascular benefits of the diabetes drug dapagliflozin extend across a wide spectrum of patients and are especially pronounced in those with reduced ejection fraction, according to new research.Reduced ejection fraction is a measure of the heart’s pumping ability indicative of poor heart functioning.
The findings come from the DECLARE-TIMI 58 trial, which reported in
Award-winning American game show host of “Jeopardy!” Alex Trebek announced his diagnosis with stage IV pancreatic cancer earlier this month.Just like him, 56,000 Americans will be diagnosed with pancreatic cancer this year.Pancreatic cancer is a leading cause of cancer-related death in the U.S. with a very low survival rate. The symptoms of this form of cancer are not obvious
Aerpio Pharmaceuticals, a company focused on developing drugs to treat ocular diseases and diabetic complications, today announced top-line results from a phase 2b clinical trial of Aerpio’s lead candidate, AKB-9778, for patients with moderate to severe non-proliferative diabetic retinopathy (NPDR).
The company announced that administering AKB-9778 twice daily did not meet the study’s primary
Americans looking to be more healthy can exercise in smaller segments in shorter bursts of time, according to new guidelines released by the government on Monday.The new recommendations come 10 years after the first guidelines were released by the U.S. Department of Health and Human Services 2008.
The panel noted that the benefits of movement reduce
A recent Australian study finds that older patients with diabetes may struggle more with verbal memory and fluency than those without diabetes.Scientists have known a link between cognitive decline and diabetes exists in older patients, but according to Dr. Michele L. Callisaya, one of the study authors, “it is still not entirely clear why people with T2D
Fecal transplants are a routine treatment for nasty recurrent diarrheal infections, but trials for other conditions have hit a bum note.Now, researchers are re-examining the full potential of such transplants for restoring gut chemicals that are lacking in illnesses like IBD and diabetes, according to a new study.
“The last two decades have seen a
People who suffer from obesity and Type 2 diabetes are more likely to become victims of infectious diseases, according to researchers in Brazil.The reason for this is because both conditions affect the immune system. Scientists have long sought a deeper understanding of the mechanism underlying this weakness in the immune system of obese and diabetic individuals.
Diabetes is a global pandemic. One in 11 adults has diabetes and in 2040, 1 in 10 adults will have diabetes. It is one of the most important global public health challenges today. Gestational diabetes affects up to 14% of pregnancies worldwide and 18 million births every year. It has several complications during pregnancy
Green tea cut obesity and a number of inflammatory biomarkers linked with poor health in a new study. Mice fed a diet of 2 percent green tea extract fared far better than those that ate a diet without it, a finding that has prompted an upcoming study of green tea’s potential benefits in people at
Women who find their jobs mentally tiring are more likely to develop Type 2 diabetes, according to a study published in the European Journal of Endocrinology.The study findings suggest that mentally draining work, such as teaching, may increase the risk of diabetes in women. This suggests that employers and women should be more aware of the